[Basel Computational Biology Conference 2008]

Protein   Program


Conference Schedule:


Thursday, March 13, 2008

    Registration (open from 8:00)

Conference Opening & Organizer's Welcome
Torsten Schwede & Manuel Peitsch
(Biozentrum University Basel & Swiss Institute of Bioinformatics)

Ron Appel (Swiss Institute of Bioinformatics)


Opening Keynote Lectures:
Arthur Lesk (Penn State University, USA)
"Vertical and Horizontal Relationships Among Protein Folding Patterns"
Malcolm Weir (Heptares Therapeutics, UK)
"Computational Structural Biology in Drug Discovery"





Coffee Break



Session I: Protein Function
David Jones (University College London, UK)
"Combining Structural and Sequence-Based Features for Improved Protein Function Prediction"
Andrei Lupas (MPI for Developmental Biology, Tübingen, Germany)
"From Bioinformatics to Structure: Insight into the Mechanism of Transmembrane Signal Transduction"





Lunch Break



Session II: Experimental approaches to structural biology
Michael Nilges (Institut Pasteur, Paris, France)
"Bayesian Structure Calculation"
Markus Grütter (University of Zürich, Switzerland)
“Frontiers in X-ray Crystallography”
Andreas Engel (SystemsX.ch & Biozentrum University of Basel, Switzerland)
“What Transmission Electron Microscopes Can Visualize Now and in the Future”





Coffee Break



Session III: Protein Modeling
Andrej Sali (University of California San Francisco)
“Integrating Diverse Data for Structure Determination of Macromolecular Assemblies”
Francisco Melo (Pontificia Universidad Catolica de Chile )
"Scoring Functions for Protein Structure Prediction"
Torsten Schwede & Manuel Peitsch (Biozentrum University Basel & Swiss Institute of Bioinformatics)
“15 Years of Swiss-Model”





Conference Apero


21:00 - late  



Friday, March 14, 2008


Registration (open from 8:00)


Session IV: Molecular Dynamics
Markus Meuwly (University of Basel, Switzerland)
“Atomistic Simulations in Structural Biology”
Simon Bernèche
(Swiss Institute of Bioinformatics & University of Lausanne, Switzerland)
“Modeling and Simulation of Ion Channels”
Qiang Cui
(University of Wisconsin, USA)
“Functional Motions in Biomolecules: Insights from Computational Studies at Multiple Scales”

István Kolossváry (D.E. Shaw Research)

"Novel algorithms in Desmond enabling practical microsecond-scale molecular dynamics simulations in the Maestro environment"





Coffee Break 



Session V: RNA structure prediction and dynamics
François Major (University of Montréal, Canada)
“RNA Tertiary Structure Prediction Using the MC-Fold – MC-Sym Pipeline”
Fabrice Jossinet (Université Louis Pasteur, Strasbourg, France)
"PARADISE: A Bioinformatics Framework to Construct RNA 3D Models"





Lunch Break 



Session VI: Protein Ligand Interactions
Richard Friesner (Columbia University, New York, USA)
“Small Molecule Docking”
Angelo Vedani
(Biographics Laboratory 3R & University of Basel, Switzerland)
“VirtualToxLab — Predicting the Toxic Potential of Drugs and Environmental Chemicals in Silico”
Michael Podvinec (Swiss Institute of Bioinformatics & Biozentrum, University of Basel, Switzerland)
“Docking for Neglected Diseases as Community Efforts”


Closing Keynote Lecture:

Sir Tom Blundell (School of Biological Sciences, University of Cambridge, UK)
"Structural Bioinformatics and Drug Discovery: Exploring Chemical and Biological Space"


Conference Closing Remarks

ca. 16:45  

End of conference