In the spring of 2007, Basel will host a major scientific meeting for all scientists engaged in biological research in Switzerland, the USGEB or Annual Meeting of the Union of Swiss Societies for Experimental Biology. Because 2007 marks the 300th anniversary of the birth of Euler, one of Basel's most famous mathematicians, we have chosen the theme "Mathematics in Biology" for this two day event. We are organizing this together with the Basel Computational Biology Conference which normally sponsors a workshop each year on computational biology. This joint conference will be held on March 13-14, 2007 at the Messe Basel. We expect roughly a 1000 participants, from all Swiss universities and research institutes. The meeting will include 10 plenary lectures on topics ranging from process maps through proteomics to mathematical epidemiology. Eleven minisymposia (called workshops) will host another 30-40 speakers on different biological themes. In all cases, we have made the effort to integrate mathematicians, computational biologists, modelers and bioinformaticians, so that the meeting will fulfill our aim of demonstrating and exploring quantitative aspects of biological research. This theme is highly appropriate given that ETHZ has just opened an institute of Systems Biology and Engineering (D-BSSE) here in Basel. We count on the participation of many scientists actively engaged in systems biology research, and expect to awaken the interest of many others who have not yet explored this approach. We count on the science being cutting edge at this trail-blazing meeting.