[BC]2 - Basel Computational Biology Centre
The Basel Computational
Biology Centre [BC]2 is a collaborative effort between
academic biomedical and pharmaceutical research institutes in Basel.
The goal of this collaboration is to share knowledge, resources,
and services in an effort to create a center of excellence in the
field of computational biology and bioinformatics. It is hoped that
this effort will serve as a framework to encourage collaborations
and the exchange of ideas at all levels in the scientific community.
Current member institutions are: The Biozentrum
of the University of Basel, the Friedrich Miescher
Institute and the Swiss Institute of Bioinformatics.
Review previous [BC]2
years ago, at a time when biology was still considered a “soft”
science and chemistry and physics were the leading “hard”
sciences it was a courageous and visionary decision to create the
as a center of excellence, devoted exclusively to biology. For the
next 15 years the “Biozentrum” would remain the first
and only such center world-wide. The success of the Biozentrum,
gaining high international visibility in only a few years, attests
primarily to the scientific quality of its research groups. This
was helped, however, by bringing together under one roof apparently
unrelated fields such as chemistry, physics, microbiology, cell
biology, biochemistry, and pharmacology and to create an amalgam
of these sciences with biology.
2002, the University of Basel and the Swiss
Institute of Bioinformatics (SIB) launched a collaborative effort
to establish Bioinformatics
as a new division at the Biozentrum to establish an internationally
competitive research and teaching program in this key area of current
biological sciences. Currently, the Biozentrum's
Core Program Genome Scale Biology & Bioinformatics is formed
by six research groups: Urs
Meyer (Pharmacogenomics), Peter
Philippsen (Genomics based Fungal Biology),
Mihaela Zavolan (Computational Biology of RNA), Erik
van Nimwegen (Genome Systems Biology), Michael
Primig (Genome Annotation and Regulatory Networks), and Torsten
Schwede (Protein Structure Bioinformatics).
||FMI - Friedrich Miescher Institute
Friedrich Miescher Institute is
devoted to fundamental biomedical research, employing new technologies
to explore basic molecular mechanisms of cells and organisms in
health and disease. Current research focuses on the fields of epigenetics,
growth control and neurobiology. The FMI has not only initiated
key developments in molecular biology over the years but has also
provided young scientists from all over the world with an opportunity
to participate in scientific research. This lively educational establishment
has trained hundreds of young scientists at the postgraduate and
postdoctoral levels. Many of the FMI research group leaders hold
the title of Privatdozent or Titular Professor at the University
of Basel. The FMI is part of the Novartis Research Foundation and
is also the recipient of numerous grants from national and international
||SIB - Swiss Institute
of Bioinformatics (SIB) is an academic non-profit foundation
established in 1998. The SIB's mission is to promote research, teaching
and service activities in the field of bioinformatics within the
framework of national and international collaborations. Members
of the SIB include research groups in Geneva, Lausanne and Basel.
The SIB expertise is widely appreciated and its services are used
worldwide by researchers in cellular and molecular biology.
SIB maintains databases of international standing (e.g. Swiss-Prot,
Prosite, EPD, Swiss-2Dpage, Hits, Swiss Model Repository). It supplies
and develops services for the biomedical research community worldwide
by way of software and services that can be accessed from the SIB
web servers (e.g. ExPASy,
Melanie, T-COFFEE, PFTOOLS, Swiss-Model).
It supplies services to the Swiss biomedical research community
within the framework of the international network EMBnet.